Anti-CD61 (β3, GPIIIa) 

Antigen CD61, also known as β3 subunit, is an integrin family protein that pairs with αIIb or αV subunits, which is important for both outside-in and inside-out signalingcontributing to cell adhesion. αIIbβ3 integrin (i.e. glycoprotein (GP) IIbIIIa) is the central receptor of platelet aggregation. αVβ3 integrin plays a critical role in angiogenesis.  Our anti-CD61 monoclonal antibodies are generated inhybridoma cells isolated from β3 knockout mice immunized with purified recombinant human β3 integrin.

DEC A

Reactivity

Application 

Clonality

Synonyms

Human, mouse, rat and pig

IF, IHC, FC

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

HUTA A

Reactivity

Application 

Clonality

Synonyms

Human

IF, IHC, FC, WB (non-reducing)

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

HUTA D

Reactivity

Application 

Clonality

Synonyms

Human, mouse

IF, IHC, FC, WB (non-reducing)

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

9D2

Reactivity

Application 

Clonality

Synonyms

Human, mouse, rat and pig

IF, IHC, FC

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

M1

Reactivity

Application 

Clonality

Synonyms

Human, mouse, rat and pig

IF, IHC, FC

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

JAN A

Reactivity

Application 

Clonality

Synonyms

Mouse

IF, IHC, FC

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

JAN D

Reactivity

Application 

Clonality

Synonyms

Human, mouse, rat and pig

IF, IHC, FC

Monoclonal

αIIbβ3, GPIIbIIIa, αVβ3, CD61

Product Table at-a-glance

Characterization of anti-β3 integrin monoclonal antibodies

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β3-/- mice were immunized with wild-type mouse platelets or purified human β3 integrin. Isotype and binding to platelets were analyzed by a flow cytometric assay by using washed platelets pre-incubated with 5ug/mL of monoclonal antibodies and then incubated with FITC-conjugated anti-mouse -IgG, -IgG1, -IgG2a, -IgG2b and IgG3. M: mouse, H: human, R: rat, P: pig