About Us
CCOA Biotechnology is a state-of-the-art technology platform operating within CCOA Therapeutics Inc. that provides life science services, diagnostics and research reagents. Housed at Unity Health Toronto, St. Michael's Hospital, CCOA Biotechnology generates high-quality antibodies, kits and reagents for research use which have been utilized in many high impact publications for over twenty years.
Products
Anti-CD42b (GPlbα)
Glycoprotein Ibα (GPIbα), also known as CD42b, is a component of the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet plug formation at sites of vascular injury. These anti-CD42b monoclonal antibodies are generated in hybridoma cells isolated from GPIbα knockout mice immunized with wild-type mouse platelets.
Anti-CD61 (β3, GPIIIa)
Antigen CD61, also known as β3 integrin, is an integrin family protein comprised of αIIb/αV and β3 subunits that performs both outside-in and inside-out signalling contributing to cell adhesion. Our anti-CD61 monoclonal antibodies are generated in hybridoma cells isolated from β3 knockout mice immunized with purified recombinant human β3 integrin.
Services
Molecular Cloning
Antibody epitope mapping
Stable cell line generation
Transfection-grade plasmid preparation
Antibody affinity maturation
Custom Antibody Development
Antibody humanization
Antigen
production