About Us
CCOA Biotechnology is a state-of-the-art technology platform operating within CCOA Therapeutics Inc. that provides life science services, diagnostics and research reagents. Housed at Unity Health Toronto, St. Michael's Hospital, CCOA Biotechnology generates high-quality antibodies, kits and reagents for research use which have been utilized in many high impact publications for over twenty years.
![IMG-9034.jpg](https://static.wixstatic.com/media/be8f5b_8b0d10eac38d4c0da8a6c7a422536bef~mv2.jpg/v1/fill/w_470,h_250,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/IMG-9034.jpg)
Products
Anti-CD42b (GPlbα)
Glycoprotein Ibα (GPIbα), also known as CD42b, is a component of the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet plug formation at sites of vascular injury. These anti-CD42b monoclonal antibodies are generated in hybridoma cells isolated from GPIbα knockout mice immunized with wild-type mouse platelets.
Anti-CD61 (β3, GPIIIa)
Antigen CD61, also known as β3 integrin, is an integrin family protein comprised of αIIb/αV and β3 subunits that performs both outside-in and inside-out signalling contributing to cell adhesion. Our anti-CD61 monoclonal antibodies are generated in hybridoma cells isolated from β3 knockout mice immunized with purified recombinant human β3 integrin.
Services
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Molecular Cloning
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Antibody epitope mapping
![](https://static.wixstatic.com/media/5bfb6f_5b3bff9a8dc149e8ada5f665bc60da44~mv2.png/v1/fill/w_79,h_79,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/5bfb6f_5b3bff9a8dc149e8ada5f665bc60da44~mv2.png)
Stable cell line generation
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Transfection-grade plasmid preparation
![](https://static.wixstatic.com/media/5bfb6f_3150d8a22c9a4b7b9f0839d437482bf1~mv2.png/v1/fill/w_79,h_79,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/5bfb6f_3150d8a22c9a4b7b9f0839d437482bf1~mv2.png)
Antibody affinity maturation
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Custom Antibody Development
![](https://static.wixstatic.com/media/5bfb6f_9cc6931fc07c4c46b50694d9062d80d8~mv2.png/v1/fill/w_79,h_79,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/5bfb6f_9cc6931fc07c4c46b50694d9062d80d8~mv2.png)
Antibody humanization
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Antigen
production
Publications
Corporate News
Sponsors
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