Next Generation

Diagnostics

About Us

CCOA Biotechnology is a state-of-the-art technology platform operating within CCOA Therapeutics Inc. that provides life science services, diagnostics and research reagents. Housed at Unity Health Toronto, St. Michael's Hospital, CCOA Biotechnology generates high-quality antibodies, kits and reagents for research use which have been utilized in many high impact publications for over twenty years.

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Products

Anti-CD41 (αllb integrin,GPllb)

 

Our unique anti-CD41 monoclonal antibodies are generated in human αIIb transgenic mice immunized with wild-type mice platelets or in C57 wild-type mice immunized with human αIIb transgenic mice platelets.

Anti-CD42b (GPlbα)

 

Glycoprotein Ibα (GPIbα), also known as CD42b, is a component of the GPIb-V-IX complex on platelets. The GPIb-V-IX complex binds von Willebrand factor, allowing platelet adhesion and platelet plug formation at sites of vascular injury. These anti-CD42b monoclonal antibodies are generated in hybridoma cells isolated from GPIbα knockout mice immunized with wild-type mouse platelets. 

Anti-CD61 (β3, GPIIIa) 

 

Antigen CD61, also known as β3 integrin, is an integrin family protein comprised of αIIb/αV and β3 subunits that performs both outside-in and inside-out signalling contributing to cell adhesion. Our anti-CD61 monoclonal antibodies are generated in hybridoma cells isolated from β3 knockout mice immunized with purified recombinant human β3 integrin.

Hand Sanitizer

 

Contains 80% alcohol which is strongly recommended by WHO and Health Canada for increased antiseptic efficacy

Can effectively and quickly kill viruses, germs, and fungi

 

Non-toxic, non-irritating, and does not hurt hands with highest quality of alcohol and glycerol

Services

Molecular Cloning

Antibody epitope mapping

Stable cell line generation

Transfection-grade plasmid preparation

Antibody affinity maturation

Custom Antibody Development

Antibody humanization

Antigen

 production

Publications

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Plasma fibronectin depletion enhances platelet 

aggregation and thrombus formation in mice lacking fibrinogen and von Willebrand factor

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Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

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GPIbα is required for platelet-mediated hepatic

thrombopoietin generation

Corporate News

2020-04-08
2020-03-16

Sponsors

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